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Pioneer Labs

Fragments / Research guide

SNAP-8.

A little deeper. A clearer picture.

A peptide name associated with acetyl octapeptide-3 in cosmetic-ingredient records. The name of a cosmetic ingredient and the specification of a research powder answer different questions.

For research use onlyView SNAP-8 sizes
Published by Pioneer LabsUpdated Sources & editorial standards

01 / Reference identity

Identity at a glance.

Public records list SNAP-8 as acetyl octapeptide-3: one eight-residue chain with both ends modified, an acetyl group at the N-terminus and an amide at the C-terminus. The formula and weight below include both end groups; the salt form of a supplied lot follows its own record.

SNAP-8 reference identity
Sequence, three-letterAc–Glu–Glu–Met–Gln–Arg–Arg–Ala–Asp–NH₂
Sequence, one-letterAc-EEMQRRAD-NH₂
Length8 residues
End groupsN-terminal acetyl, C-terminal amide
Formula, acetylated and amidatedC41H70N16O16S
Molecular weight1075.2 g/mol
CAS number868844-74-0
PubChem CID76283482
Other names in public recordsAcetyl octapeptide-3
Reference values from public records, not a Pioneer lot specification.

References: [2]

02 / Molecular architecture

A closer look at the chain.

Octapeptide denotes an eight-residue chain, while acetyl identifies a terminal modification. The public record gives the chain as Glu–Glu–Met–Gln–Arg–Arg–Ala–Asp, with an acetylated N-terminus and an amidated C-terminus: the residue sequence and terminal chemistry, not only the shortened name SNAP-8.

Pioneer / Reference notesMolecular features
  • 8 residues
  • Acetylated N-terminus
  • Amidated C-terminus
  1. Glu
  2. Glu
  3. Met
  4. Gln
  5. Arg
  6. Arg
  7. Ala
  8. Asp
Ac-EEMQRRAD-NH₂ reference sequence, read from the N-terminus; the acetyl group and the amide are end groups, not residues. Salt form must be checked separately.

Reference information: [1][2]. Actual lot identity must be verified separately.

Separating an ingredient name from a formulation.

SNAP-8 appears in records for a formulated cosmetic ingredient associated with acetyl octapeptide-3. A finished solution contains more formulation information than the peptide name alone. Its concentration and other specifications should not be transferred to a separately supplied research powder.

What the longer chemical name explains.

Octapeptide identifies an eight-residue peptide, while acetyl identifies a chemical modification. Those words provide useful structural clues without specifying every residue or formulation detail. The identity record, rather than the abbreviated trade name, is the place to resolve the complete molecular description.

Structure and research references: [1][2]

03 / Read the evidence

Research & analytical context.

The linked manufacturer record concerns a formulated peptide solution. It is useful for tracing the ingredient name, but does not establish performance, concentration or stability for a separate lyophilized research material.

Read the references: [1][2].

The distinction that matters

A formulated cosmetic ingredient and a raw research powder have different specifications. Confirm the peptide sequence, terminal chemistry and supplied form directly from the material record.

04 / From reference to record

Know the lot, too.

A publication describes its own test material. Your lot’s certificate describes what was tested on that lot. Keep the compound name, batch number and reported methods together when reviewing a result.

Identity & composition

Check sequence or chemical form, terminal modifications, counterion and—where relevant—each blend component.

Analytical results

Read purity, content, sterility and endotoxin results as separate measurements. Only call a test passed when the actual report supports it.

Handling & storage notes

Lyophilized material: Store at −20°C; protect from light and moisture.

Follow the material-specific label and supporting storage documentation. These temperatures do not establish a shelf life.

How to store lyophilized peptides

05 / Reference questions

A few details, explained.

Does a solution specification apply to the powder?

Not automatically. A formulated solution and a lyophilized material have different specifications. Concentration or stability information must belong to the actual material being described.

Does acetyl count as a ninth residue?

No. It is a chemical modification rather than another amino acid in the octapeptide count. Residue number and terminal modifications are separate parts of the identity.

Read alongside the references: [1][2]

06 / Continue reading

Go to the source.