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Pioneer Labs

Short peptides / Research guide

Epithalon.

A little deeper. A clearer picture.

Four amino acids in the sequence Ala–Glu–Asp–Gly. Epithalon is also spelled Epitalon in reference records.

For research use onlyView Epithalon sizes
Published by Pioneer LabsUpdated Sources & editorial standards

01 / Naming

Two spellings, one sequence.

Epithalon and Epitalon are two spellings of one name. PubChem lists both, with Epithalone, as synonyms of a single record (CID 219042), and the cited Cayman record uses Epitalon. Each names the same four-residue chain, Ala–Glu–Asp–Gly, abbreviated AEDG.

Epithalon reference identity
Names in public recordsEpithalon, Epitalon, Epithalone
SequenceAla–Glu–Asp–Gly (AEDG)
Length4 residues
Formula, free peptideC14H22N4O9
Molecular weight, free peptide390.35 g/mol
PubChem CID219042
Reference values from public records, not a Pioneer lot specification.

References: [1][2]

02 / Molecular architecture

A closer look at the chain.

The sequence Ala–Glu–Asp–Gly is abbreviated AEDG. Two adjacent acidic amino acids make this short sequence easy to distinguish from other small peptides with similar commercial names.

Pioneer / Reference notesMolecular features
  • 4 amino acids
  • AEDG
  • Two adjacent acidic residues
  1. Ala
  2. Glu
  3. Asp
  4. Gly
AEDG reference sequence; terminal chemistry and salt form must be checked separately.

Reference information: [1][2]. Actual lot identity must be verified separately.

Reading AEDG from left to right.

AEDG uses the one-letter amino-acid codes for alanine, glutamate, aspartate and glycine. Sequence notation is read from the N-terminus toward the C-terminus. The order matters: a peptide containing those same four residues in another order would have a different backbone identity.

Two adjacent acidic side chains.

Glutamate and aspartate sit next to each other in this reference sequence. Their side chains contain carboxyl groups, while alanine and glycine provide different side-chain structures. This is a chemical description of the backbone’s building blocks; it does not specify the pH of a solution or the counterion in a supplied powder.

Structure and research references: [1]

03 / Read the evidence

Research & analytical context.

The chemical reference lists the AEDG sequence and separately identifies its salt form. The peptide backbone and the counterion are different parts of the specification; a sequence drawing does not identify which salt a particular lot contains.

Read the references: [1][2].

The distinction that matters

Epithalon and Pinealon have different residue sequences despite their similar names. Use the complete identity record when comparing molecular mass or analytical results.

04 / From reference to record

Know the lot, too.

A publication describes its own test material. Your lot’s certificate describes what was tested on that lot. Keep the compound name, batch number and reported methods together when reviewing a result.

Identity & composition

Check sequence or chemical form, terminal modifications, counterion and—where relevant—each blend component.

Analytical results

Read purity, content, sterility and endotoxin results as separate measurements. Only call a test passed when the actual report supports it.

Handling & storage notes

Lyophilized material: Store at −20°C; protect from light and moisture.

Follow the material-specific label and supporting storage documentation. These temperatures do not establish a shelf life.

How to store lyophilized peptides

05 / Reference questions

A few details, explained.

Are Epithalon and Epitalon different sequences?

Those spellings are used for the AEDG reference. Comparing the sequence is more informative than comparing spelling alone. The chemical form and terminal groups should still be checked separately.

How is it different from Pinealon?

Epithalon is the four-residue AEDG sequence. Pinealon is the three-residue EDR sequence. Similar names and some shared residue types do not make the chains identical.

Read alongside the references: [1]

06 / Continue reading

Go to the source.