01 / Comparison
Two species forms, side by side.
Public records list two forms of Kisspeptin-10 that differ at one position. The human form ends Arg–Phe–NH₂; the mouse and rat form ends Arg–Tyr–NH₂. Both are ten residues with an amidated C-terminus. These values do not establish which form a Pioneer lot contains.
| Human form | Mouse and rat form | |
|---|---|---|
| Sequence, one-letter | YNWNSFGLRF-NH₂ | YNWNSFGLRY-NH₂ |
| Sequence, three-letter | Tyr–Asn–Trp–Asn–Ser–Phe–Gly–Leu–Arg–Phe–NH₂ | Tyr–Asn–Trp–Asn–Ser–Phe–Gly–Leu–Arg–Tyr–NH₂ |
| Length | 10 residues | 10 residues |
| Residue 10 | Phe, amidated | Tyr, amidated |
| Formula, amidated peptide | C63H83N17O14 | C63H83N17O15 |
| Molecular weight | 1302.4 g/mol | 1318.4 g/mol |
| CAS number | 374675-21-5 | 478507-53-8 |
| PubChem CID | 25240297 | 90488921 |
02 / Molecular architecture
A closer look at the chain.
The human reference is the amidated decapeptide Tyr–Asn–Trp–Asn–Ser–Phe–Gly–Leu–Arg–Phe. Species matters: the commonly listed rodent sequence has a different final residue.
- 10 residues
- KISS1R / GPR54
- Species-specific reference
- 1Tyr
- 2Asn
- 3Trp
- 4Asn
- 5Ser
- 6Phe
- 7Gly
- 8Leu
- 9Arg
- 10Phe
Reference information: [1][2][3][4]. Actual lot identity must be verified separately.
A short chain with a specified ending.
Kisspeptin-10 denotes a ten-residue peptide, but the complete identity also includes its terminal residue and amidation. The Phe–NH₂ ending in the reference shown here is not fully represented by writing only Phe. Sequence length, residue order and terminal chemistry provide complementary information.
Two names for the receptor.
KISS1R and GPR54 appear as names for the receptor in the linked research context. Recognizing that naming relationship helps trace references. Receptor naming is separate from defining the peptide: a shared target does not demonstrate that two differently specified kisspeptin materials are chemically identical.
03 / Read the evidence
Research & analytical context.
The technical reference characterizes receptor agonist activity. A receptor assay is a defined experimental readout and should not be converted into an unqualified reproductive or hormonal outcome.
Read the references: [1][2][3][4].
The distinction that matters
Confirm the terminal residue and amidation, not just the name Kisspeptin-10. Human and rodent reference materials should not be silently substituted in a protocol or comparison.
04 / From reference to record
Know the lot, too.
A publication describes its own test material. Your lot’s certificate describes what was tested on that lot. Keep the compound name, batch number and reported methods together when reviewing a result.
Identity & composition
Check sequence or chemical form, terminal modifications, counterion and—where relevant—each blend component.
Analytical results
Read purity, content, sterility and endotoxin results as separate measurements. Only call a test passed when the actual report supports it.
Handling & storage notes
Lyophilized material: Store at −20°C; protect from light and moisture.
Follow the material-specific label and supporting storage documentation. These temperatures do not establish a shelf life.
How to store lyophilized peptides05 / Reference questions
A few details, explained.
Is every Kisspeptin-10 reference the same sequence?
No. Species-reference sequences can differ, including at the final residue. The complete identity record matters even when two listings share the same short name and chain length.
What does the 10 specify?
It specifies the ten-residue peptide designation. It is separate from the material’s amount in milligrams and does not describe a result from a receptor assay.
06 / Continue reading
Go to the source.
Each source is labeled by its type. External sources are not Pioneer batch certificates.
- Tocris / R&D Systems · Human Kisspeptin-10 referenceSupplier reference · Read source (opens a new tab)
- Cayman Chemical · Rodent Kisspeptin-10 comparisonSupplier reference · Read source (opens a new tab)
- PubChem · Kisspeptin-10, human form, identity record, CID 25240297Public record · Read source (opens a new tab)
- PubChem · Kisspeptin-10, mouse and rat form, identity record, CID 90488921Public record · Read source (opens a new tab)