This page compares BPC-157 and TB-500 by what a record can show: chain length, sequence and public identifiers.
BPC-157 vs TB-500, side by side.
| BPC-157 | TB-500 | |
|---|---|---|
| Chain length | 15 amino acids | 43 amino acids |
| Sequence, one-letter | GEPPPGKPADDAGLV | On the lot’s own record |
| Formula, free peptide | C62H98N16O22 | None listed |
| Molecular weight, free peptide | 1419.5 g/mol | None listed |
| CAS number | 137525-51-0 | None listed |
| Public record | PubChem CID 9941957 (opens a new tab) · FDA UNII 8ED8NXK95P (opens a new tab) | None listed |
| Research guide | BPC-157 guide | TB-500 guide |
BPC-157: a sequence on public record.
PubChem and the FDA’s substance registry both record BPC-157 as one chain of 15 residues, GEPPPGKPADDAGLV, read from the N-terminus.
Three prolines sit together at positions 3–5 and a fourth at position 8. Two aspartates sit side by side at positions 10–11. There is no cysteine, so the chain has no disulfide bridge.
The formula and molecular weight in the table are PubChem’s, for the free peptide. The salt form of a supplied lot follows its own record.
TB-500: one name, two molecules.
Pioneer’s TB-500 is the 43-amino-acid form, the same length as thymosin beta-4. Its full sequence, the chemistry at each end and its salt form belong to the lot’s own record, so the table gives no sequence, formula or molecular weight for it.
In one analytical study, TB-500 is Ac-LKKTETQ: a seven-residue fragment with an acetylated N-terminus. Those seven residues are positions 17–23 of mature thymosin beta-4, a 43-residue chain.
So a record that says only TB-500 could mean the seven-residue fragment or the 43-amino-acid form. Check its chain length before setting it beside BPC-157. The TB-500 guide covers both uses of the name.
Where both appear.
Three blends hold both. In each one they stay separate molecules, not one joined chain, and the TB-500 is the 43-amino-acid form.
- BPC-157 + TB-5005mg BPC-157 and 5mg TB-500 in a 10mg vial.
- BPC-157 + TB-50010mg BPC-157 and 10mg TB-500 in a 20mg vial.
- GLOW50mg GHK-Cu, 10mg BPC-157 and 10mg TB-500 in a 70mg vial.
- KLOW50mg GHK-Cu, 10mg BPC-157, 10mg TB-500 and 10mg KPV in an 80mg vial.
Amounts by mass, as formulated. Match your lot’s certificate to them.
What this page leaves out.
This comparison is about identity: what each molecule is, as far as a record shows it. It does not rank the two, and it does not describe how either behaves, alone or together.
A public record describes a reference molecule, and a paper describes its own test material. Your lot’s certificate is the record for the material in your vial.
Go to the source.
Each source is labeled by its type. External sources are not Pioneer batch certificates.
- PubChem · BPC-157 identity record, CID 9941957Public record · Read source (opens a new tab)
- FDA GSRS · BPC-157 substance record, UNII 8ED8NXK95PPublic record · Read source (opens a new tab)
- Ho et al. · Analytical identification of TB-500 (2012)Published research · Read source (opens a new tab)
- UniProt · Thymosin beta-4 sequence record, P62328Public record · Read source (opens a new tab)